Supported by the International Association of
Therapeutic Drug Monitoring & Clinical Toxicology
and hosted by the Polish Pharmaceutical Society and the Polish Transplantation Society.
Therapeutic Drug Monitoring & Clinical Toxicology
and hosted by the Polish Pharmaceutical Society and the Polish Transplantation Society.
Preliminary agenda:
25 September 2008 (Thursday)
14:00 - 22:00 Registration
26 September 2008 (Friday)
8:00 - 8:30 Welcome and introduction to program
8:30 - 10:00 Oral session O1, Progress in clinical transplantation
10:00 - 10:30 Coffee Break
10:30 - 12:00 Oral session O2, Basic Science for Therapeutic Drug Monitoring of Immunosuppressive Drugs
12:00 - 13:00 Oral session O3, PK/PD modelling and novel biomarkers: application in the field of transplantation
13:00 - 14:00 Lunch
14:00 - 16:00 Oral session O4, Analytical methods for immunosuppressive drugs
16:00 - 16:30 Coffee Break
16:30 Oral session O5, Tools in optimizing the immunosuppressive therapy
19:00 - 22:00 Social Event, The Royal Castle
27 September 2008 (Saturday)
8:00 - 10:00 Short oral communications - part I
10:00 - 10:30 Coffee Break
10:30 - 12:30 Oral session O6, Principles for monitoring of immunosuppressive agents
12:30 - 13:00 State of the Art Lecture, TDM of immunosuppressive drugs - future perspectives
13:00 - 14:00 Lunch
14:00 - 16:00 Short oral communications - part II
16:00 - 18:00 Oral session O7, Pharmacokinetic differences in immunosuppressive drugs dosage forms - modified release products, generics, pro-drugs.
18:00 - 19:00 Closing remarks. See you in Montreal!
19:00 Immunosuppressive Drugs Committee of the IATDM&CT meeting (members of ISD Committee and invited speakers only)
21:00 Dinner (members of ISD Committee and invited speakers only)
Scientific program in details
Friday, September 26
Welcome address (8:00 - 8:30)
Dr T. Pawiński - Co-Chair of Organizing Committee
Prof. L. Pączek - Rector of Medical University of Warsaw
Prof. J. Pachecka – Vice-President of Polish Pharmaceutical Society
Prof. W. Rowiński – President of Polish Transplantation Society
Prof. H. Maurer - President of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology
Prof. P. Wallemacq - Chairman of Immunosuppressive Drugs Committee of IATDM&CT
Session O1 (8:30 - 10:00)
Progress in clinical transplantation
Progress in clinical transplantation
- Transplantation in Poland
Prof. M. Durlik - Department of Transplantation Medicine and Nephrology, Medical University, Warsaw, Poland - Nephrotoxicity of calcineurin inhibitors.
Prof. E. Thervet - Service de Transplantation Renale, Hospital Necker, Paris, France - Clinical immunosuppression - current status.
Prof. M. Klinger - Department of Nephrology and Transplantation Medicine, Medical University, Wroclaw, Poland
Coffee break 10:00 - 10:30
Session O2 (10:30- 12:00)
Basic Science for Therapeutic Drug Monitoring of Immunosuppressive Drugs
Basic Science for Therapeutic Drug Monitoring of Immunosuppressive Drugs
- Pharmacokinetic principles of immunosuppressive drugs.
Prof. K. Budde - Department of Nephrology, Charité Campus Mitte, Humboldt-University, Berlin, Germany - Pharmacogenetics in immunotherapy: present knowledge and future perspectives.
Dr D.A. Hesselink - Department of Internal Medicine, Renal Transplant Unit, Erasmus Medical Center, Rotterdam, The Netherlands - Drug transporters for immunosuppressive agents.
Dr I.A. MacPhee - Cellular and Molecular Medicine, St. George`s Hospital, University of London, London, United Kingdom
Session O3 (12:00 - 13:00)
PK/PD modelling and novel biomarkers: application in the field of transplantation
PK/PD modelling and novel biomarkers: application in the field of transplantation
- PK/PD modelling of immunosuppressive agents.
Dr E. Wyska - Department of Pharmacokinetics and Physical Pharmacy, Collegium Medicum, Jagiellonian University, Cracow, Poland - Biomarkers as an adjunct to immunosuppressive drug monitoring.
Prof. M. Oellerich - Department of Clinical Chemistry, Georg-August-University, Gőttingen, Germany
Lunch 13:00 - 14:00
Session O4 (14h00 - 16h00)
Analytical methods for immunosuppressive drugs
Analytical methods for immunosuppressive drugs
- Introduction to HPLC-MS-MS: The gold standard for monitoring immunosuppressive drugs.
Dr P.J. Taylor - Department of Medicine, University of Queensland; Clinical Pharmacology and Australian Bioanalytical Services, Princess Alexandra Hospital, Brisbane, Australia - Review of the newest HPLC-MS-MS methods for determination of immunosuppressive drugs in clinical practice.
Dr M. Korecka - Clinical Pharmacology Laboratory, Department of Pathology & Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA - Immunoassays - benefits and risks.
Prof. W. Steimer - Institute for Clinical Chemistry and Pathobiochemistry, Munich University of Technology, Munich, Germany - What can we learn from proficiency testing of immunosuppressive drug assays?
Prof. D. Holt - The Analytical Unit, St. George`s - University of London, London, United Kingdom
Coffee break 16:00 - 16:30
Session O5 (16:30 - 17:30)
Tools in optimizing the immunosuppressive therapy
Tools in optimizing the immunosuppressive therapy
- Clinical application of population pharmacokinetic method developed for immunosuppressive agents
Prof. P. Marquet - Department of Pharmacology, University Hospital, Limoges, France - Limited sampling strategy models for pharmacokinetic studies of immunosuppressive drugs in transplant patients.
Prof. L. Shaw - Department of Pathology & Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA
Piano Concert and Gala Dinner at the Royal Castle 19:00 - 22:00
Saturday, September 27
Parallel sessions: Oral communications - part I (8:00 - 10:00)
Coffee break 10:00 - 10:30
Session O6 (10:30 - 12:30)
Principles for monitoring of immunosuppressive agents
Principles for monitoring of immunosuppressive agents
- TDM of cyclosporine.
Prof. A. Johnston - Clinical Pharmacology, Barts and The London, Queen Mary`s School of Medicine and Dentistry, London, United Kingdom - TDM of tacrolimus.
Prof. P. Wallemacq - Cliniques Universitaires St. Luc, Brussels, Belgium - TDM of sirolimus and everolimus.
Prof. É.M. Billaud - Hospital Européen Georges Pompidou, Paris, France - TDM of mycophenolic acid (mycophenolate mofetil and mycophenolate sodium).
Dr T. van Gelder - Clinical Pharmacology Unit, Erasmus Medical Center, Rotterdam, The Netherlands - Influence of interactions between immunosuppressive drugs for TDM.
Prof. D. R. J. Kuypers – Department of Nephrology and Renal Transplantation, University of Leuven, Leuven, Belgium
State of the Art Lecture (12:30 - 13:00)
- Therapeutic Drug Monitoring of immunosuppressive drugs - future perspectives.
Prof. P. Wallemacq - Cliniques Universitaires St. Luc, Brussels, Belgium
Lunch 13:00 - 14:00
Parallel sessions: Oral communications - part II (14:00 - 16:00)
Session O7 (16:00 - 18:00)
Pharmacokinetic differences in immunosuppressive drugs dosage forms - modified release products, generics, pro-drugs
Pharmacokinetic differences in immunosuppressive drugs dosage forms - modified release products, generics, pro-drugs
- Generic products - requirements for drug registration.
Dr P.K. Kunicki - Clinical Pharmacology Unit, Department of Clinical Biochemistry, National Institute of Cardiology, Warsaw, Poland - Generics of immunosuppressive drugs - requirements for an equivalent product.
Prof. A. Johnston - Clinical Pharmacology, Barts and The London, Queen Mary`s School of Medicine and Dentistry, London, United Kingdom - Modified release formulation in immunotherapy - the tacrolimus case.
Dr N. Undre - Astellas GmbH, Munich, Germany - Generics - where do we go from here?
the roundtable discussion: invited experts
Closing remarks 18:00
Dr P. K. Kunicki - Co-Chair of Organizing CommitteeProf. H. Maurer - President of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology
Immunosuppressive Drugs Committee of the IATDM&CT meeting (19:00 - 20:00)
(members of ISD Committee and invited speakers only)
(members of ISD Committee and invited speakers only)
Dinner 21:00
(members of ISD Committee and invited speakers only)
(members of ISD Committee and invited speakers only)
